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Did you mean acad and insulin resistance (1,028 results)?
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.
Matsuda J, Takahashi A, Takabatake Y, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori JY, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y. Matsuda J, et al. Autophagy. 2020 Oct;16(10):1889-1904. doi: 10.1080/15548627.2020.1712107. Epub 2020 Jan 16. Autophagy. 2020. PMID: 31944172 Free PMC article.
This study shows that sustained high autophagic flux by RUBCN deficiency in PTECs leads to metabolic syndrome concomitantly with an accelerated mobilization of phospholipids from cellular membranes to lysosomes. Abbreviations: ABC: ATP binding cassette; ACADM: acyl-CoA deh …
This study shows that sustained high autophagic flux by RUBCN deficiency in PTECs leads to metabolic syndrome concomitantly with an accelera …
Placental Fatty Acid Metabolism and Transport in a Rat Model of Gestational Diabetes Mellitus.
Mishra JS, Kumar S. Mishra JS, et al. J Womens Health Dev. 2023;6(2):56-67. doi: 10.26502/fjwhd.2644-288400108. Epub 2023 May 4. J Womens Health Dev. 2023. PMID: 37288271 Free PMC article.
Gestational diabetes mellitus (GDM) is a form of heightened insulin resistance triggered during gestation. This study examines how insulin resistance alters placental long-chain polyunsaturated fatty acid (LCPUFA) transport and metabolism in a rat mode …
Gestational diabetes mellitus (GDM) is a form of heightened insulin resistance triggered during gestation. This study examines …
The liver X receptor agonist T0901317 protects mice from high fat diet-induced obesity and insulin resistance.
Gao M, Liu D. Gao M, et al. AAPS J. 2013 Jan;15(1):258-66. doi: 10.1208/s12248-012-9429-3. Epub 2012 Nov 22. AAPS J. 2013. PMID: 23180161 Free PMC article.
Twice weekly intraperitoneal injections of T0901317 at 50 mg/kg in animals on the same diet completely blocked obesity development, obesity-associated insulin resistance, and glucose intolerance. Quantitative real-time PCR analysis showed that T0901317-treated anima …
Twice weekly intraperitoneal injections of T0901317 at 50 mg/kg in animals on the same diet completely blocked obesity development, obesity- …
Hydrodynamic delivery of interleukin 15 gene promotes resistance to high fat diet-induced obesity, fatty liver and improves glucose homeostasis.
Sun H, Liu D. Sun H, et al. Gene Ther. 2015 Apr;22(4):341-7. doi: 10.1038/gt.2014.114. Epub 2014 Dec 11. Gene Ther. 2015. PMID: 25503694
These effects are accompanied by suppressed expression of genes involved in lipogenesis and gluconeogenesis including Scd-1, Fas, Pdk4, Pepck and G6p, and enhanced expression of genes responsible for lipolysis and glucose metabolism such as Cpt1-alpha, Cpt1-beta, Acadm, Ac …
These effects are accompanied by suppressed expression of genes involved in lipogenesis and gluconeogenesis including Scd-1, Fas, Pdk4, Pepc …
Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism.
Sotelo-González AM, Reynoso-Camacho R, Hernández-Calvillo AK, Castañón-Servín AP, García-Gutiérrez DG, Gómez-Velázquez HDJ, Martínez-Maldonado MÁ, de Los Ríos EA, Pérez-Ramírez IF. Sotelo-González AM, et al. Int J Environ Res Public Health. 2023 Mar 1;20(5):4418. doi: 10.3390/ijerph20054418. Int J Environ Res Public Health. 2023. PMID: 36901426 Free PMC article.
Moreover, the strawberry beverage showed the most significant up-regulation of hepatic Cpt1 and Acadm (fatty acid beta-oxidation). In contrast, the blueberry beverage showed the most significant down-regulation of hepatic Fatp5 and Cd36 (fatty acid intracellular transport) …
Moreover, the strawberry beverage showed the most significant up-regulation of hepatic Cpt1 and Acadm (fatty acid beta-oxidation). In …
Exercise training reverses adiponectin resistance in skeletal muscle of patients with chronic heart failure.
Van Berendoncks AM, Garnier A, Beckers P, Hoymans VY, Possemiers N, Fortin D, Van Hoof V, Dewilde S, Vrints CJ, Ventura-Clapier R, Conraads VM. Van Berendoncks AM, et al. Heart. 2011 Sep;97(17):1403-9. doi: 10.1136/hrt.2011.226373. Epub 2011 Jun 16. Heart. 2011. PMID: 21685184
BACKGROUND: Resistance to the insulin-sensitising adipocytokine, adiponectin, has been described at the level of the skeletal muscle in patients with chronic heart failure (CHF). ...RESULTS: Adiponectin mRNA expression in the nine CHF patients was higher than that i …
BACKGROUND: Resistance to the insulin-sensitising adipocytokine, adiponectin, has been described at the level of the skeletal …
Zeaxanthin ameliorates obesity by activating the β3-adrenergic receptor to stimulate inguinal fat thermogenesis and modulating the gut microbiota.
Xie J, Liu M, Liu H, Jin Z, Guan F, Ge S, Yan J, Zheng M, Cai D, Liu J. Xie J, et al. Food Funct. 2021 Dec 13;12(24):12734-12750. doi: 10.1039/d1fo02863d. Food Funct. 2021. PMID: 34846398
ZEA treatment reduced body weight, fat weight, adipocyte hypertrophy, liver weight, and lipid deposition, and improved dyslipidaemia, serum GPT, GOT, leptin, and irisin levels, glucose intolerance, and insulin resistance in HFD-fed mice. Mechanistically, ZEA treatme …
ZEA treatment reduced body weight, fat weight, adipocyte hypertrophy, liver weight, and lipid deposition, and improved dyslipidaemia, serum …
Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults.
Gonzalez JT, Richardson JD, Chowdhury EA, Koumanov F, Holman GD, Cooper S, Thompson D, Tsintzas K, Betts JA. Gonzalez JT, et al. J Physiol. 2018 Feb 15;596(4):609-622. doi: 10.1113/JP275113. Epub 2017 Dec 20. J Physiol. 2018. PMID: 29193093 Free PMC article. Clinical Trial.
KEY POINTS: In lean individuals, 6 weeks of extended morning fasting increases the expression of genes involved in lipid turnover (ACADM) and insulin signalling (IRS2) in subcutaneous abdominal adipose tissue. ...In lean individuals, lipid turnover and insulin …
KEY POINTS: In lean individuals, 6 weeks of extended morning fasting increases the expression of genes involved in lipid turnover (ACADM …
iTRAQ-Based Quantitative Proteomic Comparison of 2D and 3D Adipocyte Cell Models Co-cultured with Macrophages Using Online 2D-nanoLC-ESI-MS/MS.
Lee SY, Park SB, Kim YE, Yoo HM, Hong J, Choi KJ, Kim KY, Kang D. Lee SY, et al. Sci Rep. 2019 Nov 14;9(1):16746. doi: 10.1038/s41598-019-53196-0. Sci Rep. 2019. PMID: 31727937 Free PMC article.
., PDHalpha, MDH1/2, FH) and the mitochondrial fatty acid beta oxidation pathway (e.g., VLCAD, ACADM, ECHDC1, ALDH6A1) were relatively up-regulated in the 3D co-culture model compared to those in 2D and 3D mono-cultured cells. ...These quantitative assessments showed that …
., PDHalpha, MDH1/2, FH) and the mitochondrial fatty acid beta oxidation pathway (e.g., VLCAD, ACADM, ECHDC1, ALDH6A1) were relativel …